{"id":3562,"date":"2024-04-24T17:22:21","date_gmt":"2024-04-24T09:22:21","guid":{"rendered":"https:\/\/www.360mdi.com\/archives\/3562"},"modified":"2024-04-24T17:22:21","modified_gmt":"2024-04-24T09:22:21","slug":"17%ce%b1-%e7%be%9f%e5%ad%95%e9%85%ae","status":"publish","type":"post","link":"https:\/\/www.360mdi.com\/archives\/3562","title":{"rendered":"17\u03b1-\u7f9f\u5b55\u916e"},"content":{"rendered":"<p>\u7ed3\u6784\u5f0f<\/p>\n<table class=\"summary-table table table-striped table-bordered\">\n<col width=\"90\" \/>\n<tbody>\n<tr>\n<th scope=\"row\">\u7269\u7ade\u7f16\u53f7<\/th>\n<td>01FG<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\u5206\u5b50\u5f0f<\/th>\n<td>C21H30O3<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\u5206\u5b50\u91cf<\/th>\n<td>330.46<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">\u6807\u7b7e<\/th>\n<td>\n<p>                        17\u03b1-\u7f9f\u57fa\u9ec4\u4f53\u916e,<\/p>\n<p>                        17\u03b1-\u7f9f\u57fa\u5b55\u753e-4-\u70ef-3,20-\u4e8c\u916e,<\/p>\n<p>                        \u7f9f\u57fa\u9ec4\u4f53\u916e,<\/p>\n<p>                        \u5b55\u753e-4-\u70ef-17\u03b1-\u9187-3,20-\u4e8c\u916e,<\/p>\n<p>                        17\u7f9f\u5b55\u916e,<\/p>\n<p>                        17\u0391-\u7f9f\u57fa\u9ec4\u4f53\u6fc0\u7d20,<\/p>\n<p>                        17\u0391-\u7f9f\u57fa\u5b55\u70ef\u4e8c\u916e,<\/p>\n<p>                        17-\u7f9f\u57fa\u598a\u5a20\u7d20,<\/p>\n<p>                        4-Pregnen-17\u03b1-ol-3,20-dione,<\/p>\n<p>                        17\u03b1-Hydroxy-4-pregnene-3,20-dione<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul class=\"nav nav-tabs\">\n<li class=\"active\"><a href=\"#bh\">\u7f16\u53f7\u7cfb\u7edf<\/a><\/li>\n<li><a href=\"#wx\">\u7269\u6027\u6570\u636e<\/a><\/li>\n<li><a href=\"#dl\">\u6bd2\u7406\u5b66\u6570\u636e<\/a><\/li>\n<li><a href=\"#st\">\u751f\u6001\u5b66\u6570\u636e<\/a><\/li>\n<li><a href=\"#fz\">\u5206\u5b50\u7ed3\u6784\u6570\u636e<\/a><\/li>\n<li><a href=\"#js\">\u8ba1\u7b97\u5316\u5b66\u6570\u636e<\/a><\/li>\n<li class=\"dropdown pull-right\">\n                    <a href=\"\" class=\"dropdown-toggle\" data-toggle=\"dropdown\">\u66f4\u591a <span class=\"caret\"><\/span><\/a><\/p>\n<ul class=\"dropdown-menu\" role=\"menu\">\n<li><a href=\"#xz\">\u6027\u8d28\u4e0e\u7a33\u5b9a\u6027<\/a><\/li>\n<li><a href=\"#zc\">\u8d2e\u5b58\u65b9\u6cd5<\/a><\/li>\n<li><a href=\"#hc\">\u5408\u6210\u65b9\u6cd5<\/a><\/li>\n<li><a href=\"#yt\">\u7528\u9014<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 id=\"bh\">\u7f16\u53f7\u7cfb\u7edf<\/h2>\n<p><b>CAS\u53f7\uff1a<\/b>68-96-2<\/p>\n<p><b>MDL\u53f7\uff1a<\/b>MFCD00003659<\/p>\n<p><b>EINECS\u53f7\uff1a<\/b>200-699-4<\/p>\n<p><b>RTECS\u53f7\uff1a<\/b>TU5060000<\/p>\n<p><b>BRN\u53f7\uff1a<\/b>3218109<\/p>\n<p><b>PubChem\u53f7\uff1a<\/b>24278469<\/p>\n<h2 id=\"wx\">\u7269\u6027\u6570\u636e<\/h2>\n<p>\n    \t\t1.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6027\u72b6\uff1a\u767d\u8272\u83f1\u5f62\u6216\u516d\u65b9\u5f62\u5c0f\u53f6\u72b6\u7ed3\u6676\u30022.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u5bc6\u5ea6\uff08g\/mL,25\/4\u2103\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>3.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u76f8\u5bf9\u84b8\u6c7d\u5bc6\u5ea6\uff08g\/mL,\u7a7a\u6c14=1\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>4.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u7194\u70b9\uff08\u00baC\uff09\uff1a221\u2103\uff08219-220\u2103\uff09\u3002 5.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6cb8\u70b9\uff08\u00baC,\u5e38\u538b\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>6.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6cb8\u70b9\uff08\u00baC, 5.2kPa\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>7.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6298\u5c04\u7387\uff1a90 \u00b0 (C=1, CHCl3)<\/p>\n<p>8.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u95ea\u70b9\uff08\u00baC\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>9.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6bd4\u65cb\u5149\u5ea6\uff08\u00ba\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>10.&nbsp;&nbsp;&nbsp; \u81ea\u71c3\u70b9\u6216\u5f15\u71c3\u6e29\u5ea6\uff08\u00baC\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>11.&nbsp;&nbsp;&nbsp; \u84b8\u6c14\u538b\uff08kPa,25\u00baC\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>12.&nbsp;&nbsp;&nbsp; \u9971\u548c\u84b8\u6c14\u538b\uff08kPa,60\u00baC\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>13.&nbsp;&nbsp;&nbsp; \u71c3\u70e7\u70ed\uff08KJ\/mol\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>14.&nbsp;&nbsp;&nbsp; \u4e34\u754c\u6e29\u5ea6\uff08\u00baC\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>15.&nbsp;&nbsp;&nbsp; \u4e34\u754c\u538b\u529b\uff08KPa\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>16.&nbsp;&nbsp;&nbsp; \u6cb9\u6c34\uff08\u8f9b\u9187\/\u6c34\uff09\u5206\u914d\u7cfb\u6570\u7684\u5bf9\u6570\u503c\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>17.&nbsp;&nbsp;&nbsp; \u7206\u70b8\u4e0a\u9650\uff08%,V\/V\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>18.&nbsp;&nbsp;&nbsp; \u7206\u70b8\u4e0b\u9650\uff08%,V\/V\uff09\uff1a\u4e0d\u786e\u5b9a<\/p>\n<p>19.&nbsp;&nbsp;&nbsp; \u6eb6\u89e3\u6027\uff1a \u6613\u6eb6\u4e8e\u4e59\u9187\u548c\uff0c\u6eb6\u4e8e\uff0c\u4e0d\u6eb6\u4e8e\u6c34\u3002<\/p>\n<\/p>\n<h2 id=\"dl\">\u6bd2\u7406\u5b66\u6570\u636e<\/h2>\n<p>\n    \t\t\u7e41\u6b96\uff1a\u5987\u5973\u808c\u8089\u5185TDLo\uff1a65 mg\/kgSEX\/DURATION : female 8-32 week(s) after conception\uff1b&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u5154\u5b50\u76ae\u4e0b\u6ce8\u5c04TDLo\uff1a5 mg\/kgSEX\/DURATION : female 1 day(s) pre-mating\uff1b\n    \t<\/p>\n<h2 id=\"st\">\u751f\u6001\u5b66\u6570\u636e<\/h2>\n<p>\n    \t\t\u6682\u65e0\n    \t<\/p>\n<h2 id=\"fz\">\u5206\u5b50\u7ed3\u6784\u6570\u636e<\/h2>\n<p><p>1\u3001&nbsp; \u6469\u5c14\u6298\u5c04\u7387\uff1a92.52<\/p>\n<p>2\u3001&nbsp; \u6469\u5c14\u4f53\u79ef\uff08cm<sup>3<\/sup>\/mol\uff09\uff1a286.0<\/p>\n<p>3\u3001&nbsp; \u7b49\u5f20\u6bd4\u5bb9\uff0890.2K\uff09\uff1a747.2<\/p>\n<p>4\u3001&nbsp; \u8868\u9762\u5f20\u529b\uff08dyne\/cm\uff09\uff1a46.5<\/p>\n<p>5\u3001&nbsp; \u6781\u5316\u7387\uff0810-24cm3\uff09\uff1a36.67<\/p>\n<\/p>\n<h2 id=\"js\">\u8ba1\u7b97\u5316\u5b66\u6570\u636e<\/h2>\n<p><p>1.\u758f\u6c34\u53c2\u6570\u8ba1\u7b97\u53c2\u8003\u503c\uff08XlogP\uff09:\u65e0<\/P><\/p>\n<p>2.\u6c22\u952e\u4f9b\u4f53\u6570\u91cf:1<\/p>\n<p>3.\u6c22\u952e\u53d7\u4f53\u6570\u91cf:3<\/p>\n<p>4.\u53ef\u65cb\u8f6c\u5316\u5b66\u952e\u6570\u91cf:1<\/p>\n<p>5.\u4e92\u53d8\u5f02\u6784\u4f53\u6570\u91cf:10<\/p>\n<p>6.\u62d3\u6251\u5206\u5b50\u6781\u6027\u8868\u9762\u79ef54.4<\/p>\n<p>7.\u91cd\u539f\u5b50\u6570\u91cf:24<\/p>\n<p>8.\u8868\u9762\u7535\u8377:0<\/p>\n<p>9.\u590d\u6742\u5ea6:635<\/p>\n<p>10.\u540c\u4f4d\u7d20\u539f\u5b50\u6570\u91cf:0<\/p>\n<p>11.\u786e\u5b9a\u539f\u5b50\u7acb\u6784\u4e2d\u5fc3\u6570\u91cf:6<\/p>\n<p>12.\u4e0d\u786e\u5b9a\u539f\u5b50\u7acb\u6784\u4e2d\u5fc3\u6570\u91cf:0<\/p>\n<p>13.\u786e\u5b9a\u5316\u5b66\u952e\u7acb\u6784\u4e2d\u5fc3\u6570\u91cf:0<\/p>\n<p>14.\u4e0d\u786e\u5b9a\u5316\u5b66\u952e\u7acb\u6784\u4e2d\u5fc3\u6570\u91cf:0<\/p>\n<p>15.\u5171\u4ef7\u952e\u5355\u5143\u6570\u91cf:1<\/p>\n<\/p>\n<h2 id=\"xz\">\u6027\u8d28\u4e0e\u7a33\u5b9a\u6027<\/h2>\n<p>\n    \t\t\u6682\u65e0\n    \t<\/p>\n<h2 id=\"zc\">\u8d2e\u5b58\u65b9\u6cd5<\/h2>\n<p><p>&nbsp;\u672c\u54c1\u5e94\u5bc6\u5c01\u4fdd\u5b58\u3002<\/p>\n<\/p>\n<h2 id=\"hc\">\u5408\u6210\u65b9\u6cd5<\/h2>\n<p>\n    \t\t\u6682\u65e0\n    \t<\/p>\n<h2 id=\"yt\">\u7528\u9014<\/h2>\n<p>\n    \t\t\u7528\u4e8e\u751f\u5316\u7814\u7a76\u3002\u9ec4\u4f53\u916e\u884d\u751f\u7269\u7684\u5236\u5907\u3002&nbsp;&nbsp;&nbsp;&nbsp;\n    \t<\/p>\n<p>    \t\u6269\u5c55\u9605\u8bfbhttps:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/51.jpg<\/br>\u6269\u5c55\u9605\u8bfbhttps:\/\/www.bdmaee.net\/wp-content\/uploads\/2019\/10\/1-8.jpg<\/br>\u6269\u5c55\u9605\u8bfbhttps:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/Jeffcat-DMP-Lupragen-N204-PC-CAT-DMP.pdf<\/br>\u6269\u5c55\u9605\u8bfbhttps:\/\/www.newtopchem.com\/archives\/40561<\/br>\u6269\u5c55\u9605\u8bfbhttps:\/\/www.newtopchem.com\/archives\/820<\/br>\u6269\u5c55\u9605\u8bfbhttps:\/\/www.newtopchem.com\/archives\/179<\/br>\u6269\u5c55\u9605\u8bfbhttps:\/\/www.bdmaee.net\/lupragen-n103-catalyst-dimethylbenzylamine-basf\/<\/br>\u6269\u5c55\u9605\u8bfbhttps:\/\/www.cyclohexylamine.net\/cas-23850-94-4-butyltin-tris2-ethylhexanoate\/<\/br>\u6269\u5c55\u9605\u8bfbhttps:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/-MP601-delayed-polyurethane-catalyst&#8211;delayed-catalyst.pdf<\/br>\u6269\u5c55\u9605\u8bfbhttps:\/\/www.newtopchem.com\/archives\/45087<\/br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7ed3\u6784\u5f0f \u7269\u7ade\u7f16\u53f7 01FG \u5206\u5b50\u5f0f C21H30O3 \u5206\u5b50\u91cf 330.46 \u6807\u7b7e 17\u03b1-\u7f9f\u57fa\u9ec4\u4f53\u916e, 17\u03b1-\u7f9f\u57fa\u5b55\u753e-4-\u70ef-3,20-\u4e8c\u916e, \u7f9f\u57fa\u9ec4\u4f53\u916e, \u5b55\u753e-4-\u70ef-17\u03b1-\u9187-3,20-\u4e8c\u916e, 17\u7f9f\u5b55\u916e, 17\u0391-\u7f9f\u57fa\u9ec4\u4f53\u6fc0\u7d20, 17\u0391-\u7f9f\u57fa\u5b55\u70ef\u4e8c\u916e, 17-\u7f9f\u57fa\u598a\u5a20\u7d20, 4-Pregnen-17\u03b1-ol-3,20-dione, 17\u03b1-Hydroxy-4-pregnene-3,20-dione \u7f16\u53f7\u7cfb\u7edf \u7269\u6027\u6570\u636e \u6bd2\u7406\u5b66\u6570\u636e \u751f\u6001\u5b66\u6570\u636e \u5206\u5b50\u7ed3\u6784\u6570\u636e \u8ba1\u7b97\u5316\u5b66\u6570\u636e \u66f4\u591a \u6027\u8d28\u4e0e\u7a33\u5b9a\u6027 \u8d2e\u5b58\u65b9\u6cd5 \u5408\u6210\u65b9\u6cd5 \u7528\u9014 \u7f16\u53f7\u7cfb\u7edf CAS\u53f7\uff1a68-96-2 MDL\u53f7\uff1aMFCD00003659 EINECS\u53f7\uff1a200-699-4 RTECS\u53f7\uff1aTU5060000 BRN\u53f7\uff1a3218109 PubChem\u53f7\uff1a24278469 \u7269\u6027\u6570\u636e 1.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6027\u72b6\uff1a\u767d\u8272\u83f1\u5f62\u6216\u516d\u65b9\u5f62\u5c0f\u53f6\u72b6\u7ed3\u6676\u30022.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u5bc6\u5ea6\uff08g\/mL,25\/4\u2103\uff09\uff1a\u4e0d\u786e\u5b9a 3.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u76f8\u5bf9\u84b8\u6c7d\u5bc6\u5ea6\uff08g\/mL,\u7a7a\u6c14=1\uff09\uff1a\u4e0d\u786e\u5b9a 4.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u7194\u70b9\uff08\u00baC\uff09\uff1a221\u2103\uff08219-220\u2103\uff09\u3002 5.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6cb8\u70b9\uff08\u00baC,\u5e38\u538b\uff09\uff1a\u4e0d\u786e\u5b9a 6.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&#038;nbsp [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[19],"tags":[1037],"_links":{"self":[{"href":"https:\/\/www.360mdi.com\/wp-json\/wp\/v2\/posts\/3562"}],"collection":[{"href":"https:\/\/www.360mdi.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.360mdi.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.360mdi.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.360mdi.com\/wp-json\/wp\/v2\/comments?post=3562"}],"version-history":[{"count":0,"href":"https:\/\/www.360mdi.com\/wp-json\/wp\/v2\/posts\/3562\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.360mdi.com\/wp-json\/wp\/v2\/media?parent=3562"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.360mdi.com\/wp-json\/wp\/v2\/categories?post=3562"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.360mdi.com\/wp-json\/wp\/v2\/tags?post=3562"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}